Neurogenomics & Systems Biology Laboratory

Dr. Alexandre S. Cristino is a Group Leader at the Institute for Biomedicine and Glycomics (IBG), Griffith University. His research sits at the interface of molecular biology, bioinformatics, and systems biology, with a focus on non-coding RNA regulation, gene network analysis, and multi-omics approaches applied to complex neuropsychiatric and medical conditions.

With 49 peer-reviewed publications and over 6,200 citations (h-index 29), Dr. Cristino has made significant contributions to foundational genomic studies — including the landmark Honeybee Genome Consortium (Nature, 2006) and Nasonia Genome Working Group (Science, 2010) — and has led research programs on schizophrenia, Alzheimer's disease, rare genetic disorders, and cancer immunotherapy.

Dr. Cristino's research career spans social insect genomics, neurodevelopmental biology, and translational medicine. Early work focused on establishing the genomic basis of eusociality and caste determination in honeybees at the Universidade de São Paulo, Brazil. He subsequently transitioned to mammalian neurogenomics, leading research on autism spectrum disorder and neuropsychiatric genetics at the University of Queensland, then on cancer immunology and lymphoma biomarkers at the Princess Alexandra Hospital and Translational Research Institute, before establishing the Neurogenomics and Systems Biology Laboratory at Griffith University.

His lab's current programmes address the regulatory genomics of schizophrenia, circular RNA in Alzheimer's disease and neurodegeneration, and cancer immunotherapy — bridging computational discovery with experimental validation in patient-derived cellular models.